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SCH-442416

品牌
Sigma-Aldrich
CAS
316173-57-6
货号
S6451
规格纯度
≥98% (HPLC)
参考价格
1434.12 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

SCH-442416 has been used:

  • as a selective adenosine A2A antagonist to study its effects on cyclic adenosine monophosphate (cAMP) production in T/C-28a2 chondrocytes or hFOB 1.19 osteoblasts 
  • as a presynaptic A2A receptor antagonists to study its effects on receptor blockade on δ9-Tetrahydrocannabinol (THC) self-administration in squirrel monkeys
  • as a presynaptic A2A receptor antagonists to study its effects on cocaine-induced locomotion and cocaine-seeking in mice

包装

5, 25 mg in glass bottle

生化/生理作用

SCH-442416 potent and selective Adenosine A2a antagonist. SCH-442416 is >10,000-fold selective for A2a compared to other adensosine receptors.

特点和优势

This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C20H19N7O2
分子量389.41
MDL编号MFCD08703126
PubChem化学物质编号329824564
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色light tan to tan
溶解性DMSO: ≥20 mg/mL
储存温度2-8℃
SMILES stringCOc1ccc(CCCn2ncc3c2nc(N)n4nc(nc34)-c5ccco5)cc1
InChI1S/C20H19N7O2/c1-28-14-8-6-13(7-9-14)4-2-10-26-18-15(12-22-26)19-23-17(16-5-3-11-29-16)25-27(19)20(21)24-18/h3,5-9,11-12H,2,4,10H2,1H3,(H2,21,24)
InChI keyAEULVFLPCJOBCE-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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