产品说明
生化/生理作用
SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 μM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.
基本信息
经验(实验)分子式 | C16H15FN2O4 |
分子量 | 318.30 |
MDL编号 | MFCD02219567 |
NACRES | NA.77 |
产品性质
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear |
储存温度 | 2-8℃ |
SMILES string | CCC1=CC=C(OCC(NC2=CC([N+]([O-])=O)=C(F)C=C2)=O)C=C1 |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |