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SR2595

4′-[[5-[[[(1S)-1-[4-(1,1-Dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-[1,1′-biphenyl]-2-carboxylic acid

品牌
Sigma-Aldrich
CAS
1415252-61-7
货号
SML2037
规格纯度
≥98% (HPLC)
参考价格
3481.21 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

SR2595 is an inverse agonist of PPARG (PPARγ) with an IC50 value of 30 nM. It was found to promote osteogenic differentiation of isolated bone marrow-derived mesenchymal stem cells accompanied by increased expression of bone morphogenetic proteins BMP2 and BMP6. SR2595 showed good pharmacokinetics and can be administered orally. It caused no significant change in insulin sensitivity, fasting insulin levels, food consumption or body weight when administered orally to mice.

基本信息

经验(实验)分子式C37H38N2O3
分子量558.71
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色 white to faint brown
溶解性DMSO: 2 mg/mL, clear
运输wet ice
储存温度−20℃
SMILES stringO=C(C(C=C1)=CC2=C1N(C(C)=C2C)CC(C=C3)=CC=C3C4=C(C(O)=O)C=CC=C4)N[C@H](C(C=C5)=CC=C5C(C)(C)C)C

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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