产品介绍：
产品说明
生化/生理作用
SR-301 is an orally bioavailable analog of the selective STING agonist SR-717. SR-301 shows higher potency than SR-717 by THP1-based ISRE reporter assay (EC50 = 0.6 vs. 2.1 μM, respectively) and shows good antitumor efficacy when administered orally in a murine B16.F10 melanoma tumor model in vivo (15 mg/kg/day p.o.).
基本信息
| 经验(实验)分子式 | C17H11F6N5O2 |
| 分子量 | 431.29 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 储存温度 | −20℃ |
| SMILES string | O=C(C1=NN=C(N2C=NC=C2)C=C1)NC3=C(C(O)(C(F)(F)F)C(F)(F)F)C=CC=C3 |
