产品说明
一般描述
A convenient set that offers several highly selective serine/threonine kinase inhibitors. Kinases play an important role in numerous signaling cascades. Highly selective protein kinase inhibitors are useful for dissecting these cascades to determine which specific kinases are involved in producing particular biological effects. The Serine/Threonine Kinase Inhibitor Set contains the following highly selective serine/ threonine kinase inhibitors in one convenient set:
• Bisindolylmaleimide I (Cat. No. 203290), 250 µg
• H-89, Dihydrochloride (Cat. No. 371963), 1 mg
• KN-93 (Cat. No. 422708), 1 mg
• ML-7 (Cat. No. 475880), 1 mg
• Protein Kinase G Inhibitor (Cat. No. 370654), 1 mg
• Staurosporine (Cat. No. 569397), 100 µg
包装
1 set in Glass bottle
生化/生理作用
Cell permeable: yes
Secondary Target
PKC, MLCK, Cam kinase II, PKG
Primary Target
PKA
警告
Toxicity: Multiple Toxicity Values, refer to MSDS (O)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions of each inhibitor are stable for up to 3 months at -20°C.
其他说明
Martiny, G., et al. 1993. J. Biol. Chem.268, 9194.
Toullec, D., et al. 1991. J. Biol. Chem.266, 15771.
Chijiwa, T., et al. 1990. J. Biol. Chem.265, 5267.
Simu, M., et al. 1991. Biochem. Biophys. Res. Commun.181, 968.
Saitoh, M., et al. J. Biol. Chem.262, 7796.
Glass, D.B., et al. 1983. Biochem. J.213, 159.
Seynaeve, C.M., et al. 1994. Mol. Pharmacol.45, 1207.
Meyer, T., et al. 1989. Int. J. Cancer43, 851.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
质量水平 | 100 |
形式 | solid |
manufacturer/tradename | Calbiochem® |
储存条件 | OK to freeze desiccated (hygroscopic) protect from light |
溶解性 | DMSO: 1 mg/mL (all other inhibitors) water: 1 mg/mL (Protein Kinase G Inhibitor) |
运输 | ambient |
储存温度 | −20℃ |