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Superoxide Dismutase from bovine erythrocytes

超氧化物:超氧化物氧化还原酶

品牌
Sigma-Aldrich
CAS
9054-89-1
货号
S7446
规格纯度
BioUltra, lyophilized powder, ≥4,500 units/mg protein, ≥97% (SDS-PAGE)
参考价格
2519.37 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.

应用

Superoxide Dismutase from bovine erythrocytes has been used in a study to assess activity parameters in adjuvant-induced arthritis. Superoxide Dismutase from bovine erythrocytes has also been used in a study to simplify the process of purifying superoxide dismutases using charge-controlled hydrophobic chromatography on 10-carboxydecyl Sepharose.

包装

15000, 75000 units in glass bottle

生化/生理作用

催化超氧化物自由基的歧化反应生成过氧化氢和分子氧。在细胞防御氧自由基的毒性作用方面发挥着重要作用。与一氧化氮(NO)竞争超氧化物阴离子(可与NO反应生成过亚硝酸盐),因此SOD能促进NO的活性。在培养的大鼠卵泡、神经细胞系和转基因小鼠中,SOD也表现出抑制细胞凋亡的作用。

单位定义

One unit will inhibit reduction of cytochrome c by 50% in a coupled system with xanthine oxidase at pH 7.8 at 25 ℃ in a 3.0 mL reaction volume. Xanthine oxidase concentration should produce an initial ΔA550 of 0.025 ± 0.005 per min.

基本信息

酶学委员会(EC)编号1.15.1.1 ( BRENDA | IUBMB )
EC 号232-943-0
MDL编号MFCD00132404
NACRESNA.54

产品性质

产品线BioUltra
质量水平200
测定≥97% (SDS-PAGE)
形式lyophilized powder
specific activity≥4,500 units/mg protein
分子量 32.5 kDa
组成Protein, ≥95% biuret
相关疾病arthritis
储存温度−20℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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