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Anti-Myosin-10 Antibody, clone 5H4.1

品牌
Sigma-Aldrich
货号
MABT391
规格纯度
clone 5H4.1, from mouse
参考价格
5688.25 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Myosin-10, also known as Cellular myosin heavy chain, type B, Myosin heavy chain 10, Myosin heavy chain, non-muscle IIb, Non-muscle myosin heavy chain B, NMMHC-B, Non-muscle myosin heavy chain IIb, or NMMHC-IIB, and encoded by the gene MYH10, is a myosin protein found in non-muscle cells. Often called cellular myosin, Myosin-10 appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. For instance Mysoin-10, during cell spreading, plays an important role in cytoskeleton reorganization, focal contacts and lamellipodial extension. Additionally, Myosin-10 is involved in many developmental and cellular functions including: axon guidance, retina development, cerebellar Purkinje cell layer development, exocytosis, embryonic development, mitotic cytokinesis, neuron migration, nuclear migration, regulation of cell shape, retina development, cardiac myofibril assembly, and ventricular cardiac muscle cell and adult heart development. Myosin-10 is localized to cell projections and lamellipodia. Myosin-10 is expressed in many cells and particularly in neurons in the cerebellum, spinal cord, and retina.

免疫原

GST-tagged recombinant protein corresponding to human Myosin-10.

应用

Detect Myosin-10 using this Anti-Myosin-10 Antibody, clone 5H4.1 validated for use in western blotting.
Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Myosin-10 in 10 µg of HUVEC cell lysate.

质量

Evaluated by Western Blotting in C2C12 cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected Myosin-10 in 10 µg of C2C12 cell lysate.

目标描述

~230 kDa observed. Uncharacterized band(s) may appear in some lysates.

外形

Protein G Purified
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆5H4.1, monoclonal
species reactivitymouse, human
technique(s)western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_001242941
UniProt登记号P35580
运输wet ice
Gene Informationhuman ... MYH10(4628)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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