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Anti-Peroxiredoxin 2 (C-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
R8656
规格纯度
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
参考价格
4741.12 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Peroxiredoxin 2 is a cytosolic member of the peroxiredoxin family of antioxidant enzymes. All peroxiredoxin enzymes exist as homodimers, they contain a conserved Cys residue corresponding to Cys51 in mammalian peroxiredoxin 1 and 2 and are distributed differentially within cells.

免疫原

synthetic peptide corresponding to amino acid residues 184-198 of human peroxiredoxin 2 conjugated to KLH. The corresponding sequence is identical in rat and mouse peroxiredoxin 2.

应用

Anti-Peroxiredoxin 2 (C-terminal) antibody produced in rabbit has been used in immunoblottingand immunoprecipitation.

生化/生理作用

Peroxiredoxin 2 has dual roles as a peroxireductase in moderately oxidative conditions and as a molecular chaperone that binds and protects denatured proteins in hyper-oxidative conditions. Peroxiredoxin 2 is involved in platelet-derived growth factor (PDGF) and tumor necrosis factor (TNF) signaling regulation and is elevated in several human cancers and neurodegenerative disorders.

外形

Solution in 0.01 M phophate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~22 kDa
species reactivitymouse, rat, human
浓度~1.0 mg/mL
technique(s)immunoprecipitation (IP): 2.0-5.0 μg using lysate of mouse 3T3 cells
western blot: 0.5-1.0 using whole extract of human HeLa cells
western blot: 1-2 μg/mL using whole extract of rat NRK cells
UniProt登记号P32119
运输dry ice
储存温度−20℃
Gene Informationhuman ... PRDX2(7001)
mouse ... Prdx2(21672)
rat ... PRDX2(29338)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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