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TopFluor® PI(3,4,5)P3

品牌
Avanti
CAS
2260795-37-5
货号
810189P
规格纯度
1-oleoyl-2-{12-[4-(dipyrrometheneboron difluoride)butanoyl]amino}dodecanoyl-sn-glycero-3-phosphoinositol-3,4,5-trisphosphate (ammonium salt), powder
参考价格
6618.77 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) is an inadequate phospholipid present on the inner leaflet of the plasma membrane.
PI(3,4,5)P3 (diacylphosphatidylinositol-3,4,5-trisphosphate) is restricted to the cell membrane of inner leaflet. TopFluor® PI(3,4,5)P3 is a fluorescently labeled-phosphoinositide derivative containing saturated acyl chain.

生化/生理作用

Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P3) plays a key role in inducing the cluster of Syntaxin1A at presynaptic terminals. It also regulates the activity protein kinase B/Akt.
PI(3,4,5)P3 (diacylphosphatidylinositol-3,4,5-trisphosphate) serves as a substrate for PTEN (phosphatase and tensin homolog), a tumor suppressor protein. It has binding affinity towards the active site of phosphatase domain. TopFluor® PI(3,4,5)P3 might be useful in monitoring protein induced phosphoinositide clustering. This product is considered photostable than other fluorophores.

包装

2 mL Amber Serum Vial with Stopper and Crimp Cap (810189P-50ug)

法律信息

TopFluor is a registered trademark of Avanti Polar Lipids, Inc.

基本信息

经验(实验)分子式C56H108 BF2 N7O23P4
分子量1420.19
NACRESNA.25

产品性质

测定>99% (TLC)
形式powder
包装pkg of 1 × 50 μg (with stopper and crimp cap (810189P-50ug))
manufacturer/tradenameAvanti Polar Lipids 810189P
运输dry ice
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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