产品说明
一般描述
Immunoglobulin G (IgG) is the most abundant immunoglobulin in the human serum. IgM constitutes 5-10% of total serum immunoglobulins. These immunoglobulins comprise four polypeptide chains with two heavy (H) chains and two light (L) chains. These polypeptide chains are inter-linked by disulfide bonds. IgM is a highly conserved antibody in vertebrates. IgM exists as a pentamer. Both IgG and IgM are secreted by B cells.
应用
Goat Anti-Mouse IgG & IgM Antibody, HRP conjugate has been used in western blotting(1:400) and immunofluorescence (1:500)
生化/生理作用
IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). It also aids in the activation of the classical pathway of the complement system. IgG neutralizes virus particles and toxins. IgM, an antibody that is expressed early during an immune response, aids in engulfing apoptotic cells. It exhibits polyreactive and autoreactive functionality. IgM induces tissue homeostasis by mediating the clearance of tissue-based molecules. Lower levels of IgM in serum are associated with increased autoimmune response and a higher risk of developing infections.
外形
ImmunoAffinity Purified
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.46 |
产品性质
| 质量水平 | 100 |
| 生物来源 | goat |
| 偶联物 | peroxidase conjugate |
| 抗体形式 | F(ab′)2 fragment of affinity isolated antibody |
| antibody product type | secondary antibodies |
| 克隆 | polyclonal |
| species reactivity | mouse |
| manufacturer/tradename | Chemicon® |
| 浓度 | 0.8 mg/mL |
| technique(s) | ELISA: suitable western blot: suitable |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
