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Anti-Nerve Growth Factor Receptor/TNFRSF16 antibody produced in goat

品牌
Sigma-Aldrich
货号
N6163
规格纯度
affinity isolated antibody, lyophilized powder
参考价格
4360.84 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Neurotrophins (NT) are growth factors that are essential for the development and maintenance of the nervous system. One of the receptors that mediate the effects of NTs is the Nerve Growth Factor Receptor/TNFRSF16 (p75NGFR, p75NTR). Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGFR mediates the effects of NGF that are important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. Signaling of NGF through NGFR is also implicated in inflammation and allergic reactions. Expression of NGFR has been associated with favourable prognosis and survival in breast and pancreatic cancers
Anti-Nerve Growth Factor Receptor/TNFRSF16 recognizes human NGF R.

免疫原

purified, Sf21-derived recombinant human p75 neurotrophin R extracellular domain.

应用

Anti-Nerve Growth Factor Receptor/TNFRSF16 antibody may be used for immunoblotting at a working concentration of 0.1-0.2 μg/ml.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD00282384
NACRESNA.41

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式lyophilized powder
species reactivityhuman
technique(s)western blot: 0.1-0.2 μg/mL
UniProt登记号P08138
储存温度−20℃
Gene Informationhuman ... NGFR(4804)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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