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Monoclonal Anti-Neuropilin-1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
N3287
规格纯度
clone 130603, purified immunoglobulin, lyophilized powder
参考价格
4330.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

During development, neuropilin-1 (NRP-1) is expressed in arteries. It is also a co-receptor of semaphorin-3a.

特异性

Shows no cross-reactivity with recombinant rat neuropilin-2.

免疫原

purified, NS0-derived, recombinant rat neuropilin-1.

生化/生理作用

Neuropilin-1 (NRP-1) has been shown to play an important role in vascular and neural functions. Neuropilin 1 (Nrp1) acts as a coreceptor for VEGF receptor 2 (VEGFR2) and increases the binding of VEGF165 to VEGFR2- and VEGF165-mediated chemotaxis. In transgenic mice, Nrp1 is implicated in embryonic vascular development. Elevated expression of the gene leads to the formation of excess capillaries and haemorrhaging.

外形

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

基本信息

MDL编号MFCD02097027
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆130603, monoclonal
形式lyophilized powder
species reactivityrat
technique(s)indirect ELISA: 0.5-1 μg/mL using rat Neuropilin-1
同位素/亚型IgG2b
UniProt登记号Q9QWJ9
运输wet ice
储存温度−20℃
Gene Informationrat ... Nrp1(246331)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)

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