产品说明
一般描述
Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 (Cat. No. 309825) by peroxynitrite, but does not scavenge nitric oxide (NO).
Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 µM) against paraquat (2 mM). Inhibits the oxidation of dihydrorhodamine-123 by peroxynitrite, but does not scavenge nitric oxide (NO).
包装
25 mg in Plastic ampoule
生化/生理作用
Cell permeable: yes
EC50 ~40 µM in protecting endothelial cells against paraquat (2 mM)
Product does not compete with ATP.
Reversible: no
Primary Target
Superoxide dismutase (SOD) mimetic
警告
Toxicity: Standard Handling (A)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
其他说明
Aladag, M. A., et al. 2003. Acta Neurochir.145, 673.
Szabo, C., et al. 1996. FEBS Lett. 381, 82.
Day, B.J., et al. 1995. J. Pharmacol. Exp. Ther. 275, 1227.
Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
| 经验(实验)分子式 | C48H28ClMnN4O8 |
| 分子量 | 879.15 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥95% (TLC) |
| 形式 | solid |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze desiccated protect from light |
| 颜色 | brown |
| 溶解性 | aqueous base: soluble |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
