产品介绍：
产品说明
应用
NBI 27914 has been used as acorticotropin-releasing hormone receptor (CRHR1) antagonist:
- to study its effects on steroidogenic gene expression in GD15 mouse testis
- to study its effects on amyloid β production
- to study its effects on neurogenic activity of neural stem cells in the adult hippocampus
包装
10, 50 mg in glass bottle
生化/生理作用
NBI 27914 is a CRF1 corticotropin-releasing factor receptor antagonist.
基本信息
| 经验(实验)分子式 | C18H20Cl4N4 |
| 分子量 | 434.19 |
| MDL编号 | MFCD05662281 |
| PubChem化学物质编号 | 24278425 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | solid |
| 颜色 | white |
| 溶解性 | DMSO: >20 mg/mL at 60 ℃ H2O: insoluble |
| 储存温度 | 2-8℃ |
| SMILES string | CCCN(CC1CC1)c2nc(C)nc(Nc3c(Cl)cc(Cl)cc3Cl)c2Cl |
| InChI | 1S/C18H20Cl4N4/c1-3-6-26(9-11-4-5-11)18-15(22)17(23-10(2)24-18)25-16-13(20)7-12(19)8-14(16)21/h7-8,11H,3-6,9H2,1-2H3,(H,23,24,25) |
| InChI key | KNADXBVKFAUMCR-UHFFFAOYSA-N |
| Gene Information | human ... CRHR1(1394) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
