产品说明
应用
GR 113808 has been used as a serotonin receptor 4 (5-HT4R) blocker to study its effects on the calcium (Ca2+) transients in rat ventricular cardiomyocytes. It has also been used as a 5-HT4R antagonist to study its effects on de novo enteric neurogenesis in post-embryonic zebrafish.
包装
10, 50 mg in glass bottle
生化/生理作用
GR 113808 is a 5-HT4 serotonin receptor antagonist.
特点和优势
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
法律信息
Sold for research purposes under agreement from GlaxoSmithKline
基本信息
经验(实验)分子式 | C19H27N3O4S |
分子量 | 393.50 |
MDL编号 | MFCD00912901 |
PubChem化学物质编号 | 24278311 |
NACRES | NA.77 |
产品性质
测定 | ≥98% (HPLC) |
形式 | solid |
颜色 | white to light pink |
溶解性 | DMSO: >20 mg/mL |
创始人 | GlaxoSmithKline |
储存温度 | 2-8℃ |
SMILES string | Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c3ccccc13 |
InChI | 1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3 |
InChI key | MOZPSIXKYJUTKI-UHFFFAOYSA-N |
Gene Information | human ... HTR4(3360) rat ... Htr3a(79246), Htr4(25324) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, type N95 (US) |