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p38γ, active, GST tagged human

品牌
Sigma-Aldrich
货号
G8546
规格纯度
PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
6484.55 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

p38γ, commonly known as MAPK12 (mitogen-activated protein kinase 12), is one of the four isoforms of the p38 MAPK family. This isoform shows predominant expression in skeletal muscle and is controlled by exercise.

生化/生理作用

p38γ is a key protein of the MAPK (mitogen-activated protein kinase) pathway and is involved in cell differentiation, growth, cycle and apoptosis and inflammation. It is essential for normal localization of polo-like kinase 1 (Plk1) at the kinetochore. This protein facilitates mitotic cell viability and suppresses chromosomal instability. Studies suggest that this protein negatively controls the expression of GLUT4 (glucose transporter) and the uptake of glucose mediated by contraction in adult skeletal muscles.

外形

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

法律信息

PRECISIO is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

质量水平200
重组expressed in baculovirus infected Sf9 cells
产品线PRECISIO® Kinase
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
specific activity56-76 nmol/min·mg
分子量 ~71 kDa
UniProt登记号P53778
运输dry ice
储存温度−70℃
Gene Informationhuman ... MAPK12(6300)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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