产品介绍：
产品说明
一般描述
Deoxycholic acid is an amphiphilic molecule and an important constituent of bile acid. It contains hydroxyl groups substituted at the 3α and 12α positions and a carboxyl group towards the end of the branched-chain. These moieties contribute to the hydrophilic nature of the molecule and the hydrophobic cyclopentanophenanthrene forms its center.
应用
Deoxycholic acid has been used as:
- a hyphal-inhibitory compound in an ex vivo assay to study the hyphal morphogenesis of Candida albicans in the gastrointestinal tract
- an internal standard to estimate the toxin concentration in the cell pellet
- a bile acid (BA) standard to quantitatively measure BA in various samples from treated mice by ultra-performance liquid chromatography triple quadrupole mass spectrometry
生化/生理作用
Deoxycholic acid, due to its amphiphilicity, significantly helps to solubilize, emulsify, and absorb fat, vitamins, and cholesterol in the body. High levels of intestinal deoxycholic acid might cause colorectal cancer by inducing oxidative stress and leading to DNA damage. It acts as an oncogene and pro-tumor factor.
其他说明
用于β-肾上腺素能受体的增溶
基本信息
| 经验(实验)分子式 | C24H40O4 |
| 分子量 | 392.57 |
| Beilstein | 3219882 |
| EC 号 | 201-478-5 |
| MDL编号 | MFCD00003673 |
| PubChem化学物质编号 | 329753610 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 生物来源 | ox bile |
| 描述 | anionic |
| 测定 | ≥99.0% (T) |
| 形式 | powder |
| 旋光性 | [α]20/D +54±1°, c = 1% in ethanol |
| 分子量 | 392.57 g/mol |
| 杂质 | ≤1% cholic acid (TLC) |
| mp | 170-175 ℃ 171-174 ℃ (lit.) |
| 官能团 | carboxylic acid |
| SMILES string | C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C |
| InChI | 1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1 |
| InChI key | KXGVEGMKQFWNSR-LLQZFEROSA-N |
| Gene Information | human ... ATIC(471) |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 |
| 预防措施声明 | P301 + P312 + P330 |
| 危险分类 | Acute Tox. 4 Oral |
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
