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BID, Caspase-8-cleaved from mouse

品牌
Sigma-Aldrich
货号
C4733
规格纯度
≥95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous solution
参考价格
12618.1 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Mouse BID cleaved with caspase-8 generates the amino-terminal fragment (amino acids 1-59, 7 kDa) and the carboxy-terminal fragment (amino acids 60-195, 15 kDa). On size exclusion chromatography cleaved BID elutes at 27 kDa indicating that the fragments remain associated.

生化/生理作用

Caspase-8-cleaved BID relocates from the cytosol to the outer mitochondrial membrane where its interaction with Bak alters mitochondrial membrane permeability.

外形

0.2 μm filtered solution in 25 mM HEPES, pH 7.5, and 0.1 M KCl.

分析说明

Measured by its ability to induce cytochrome c release from isolated mouse liver mitochondria.

基本信息

MDL编号MFCD03456214
NACRESNA.32

产品性质

质量水平200
重组expressed in E. coli
测定≥95% (SDS-PAGE)
形式buffered aqueous solution
UniProt登记号P70444
运输dry ice
储存温度−20℃
Gene Informationmouse ... Bid(12122)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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