位置:首页 > 品牌 > Sigma-Aldrich >

Cibenzoline succinate

Cibenzoline 琥珀酸盐

品牌
Sigma-Aldrich
CAS
100678-32-8
货号
C1618
规格纯度
≥98% (HPLC), solid
参考价格
2231.72 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Cibenzoline also called (±)-2-(2,2-diphenylcyclopropyl)-2-imidazoline succinate, is generally used in stereo combination of R(+) and S(−) forms. It also exhibits anticholinergic activity.. Cibenzoline is known to improve left ventricular diastolic dysfunction by reducing left ventricular pressure gradient.

包装

10, 50 mg in glass bottle

生化/生理作用

Cibenzoline is a class IA antiarrhythmic drug. Cibenzoline (μM concentrations) blocks ATP-sensitive K channels in heart and pancreatic cells. Cibenzoline interacts with the channel pore-forming subunit of the K(ATP) channel (Kir6.2) from the cytoplasmic side. Cibenzoline also inhibits the delayed rectifier K current [I(Kr)] in sino-atrial node cells.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C18H18N2 ·C4H6O4
分子量380.44
MDL编号MFCD00941423
PubChem化学物质编号24892426
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式solid
储存条件desiccated
颜色 white to brown
溶解性H2O: ≥5 mg/mL
储存温度2-8℃
SMILES stringOC(=O)CCC(O)=O.C1CN=C(N1)C2CC2(c3ccccc3)c4ccccc4
InChI1S/C18H18N2.C4H6O4/c1-3-7-14(8-4-1)18(15-9-5-2-6-10-15)13-16(18)17-19-11-12-20-17;5-3(6)1-2-4(7)8/h1-10,16H,11-13H2,(H,19,20);1-2H2,(H,5,6)(H,7,8)
InChI keyXFUIOIWYMHEPIE-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号