产品介绍：
产品说明
应用
Calhex 231 hydrochloride has been used:
- as a calcium-sensing receptor (CaSR) antagonist: to test its impact on hearing in rats
- to test its effect on blood pressure levels spontaneous hypertensive rats (SHRs)
- to test its effect on acoustic response bias in zebrafish
- in Caco-2 cells to test its effect on, overexpression of fibroblast growth factor-23 (FGF-23 )
包装
5, 25 mg in glass bottle
生化/生理作用
Calhex 231 is a negative allosteric modulator of the calcium sensing receptor CaSR. Calhex 231 blocks calcium-induced accumulation of inositol phosphate with an IC50 of 0.36 μM.
基本信息
| 经验(实验)分子式 | C25H27ClN2O · HCl |
| 分子量 | 443.41 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 15 mg/mL, clear |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
