产品说明
应用
SU 4312 was used to study angiogenesis during development of zebrafish embryos.2
包装
5 mg in glass bottle
生化/生理作用
SU 4312 inhibits the neuronal NOS and exhibits neuroprotection against NO-mediated neurotoxicity. It might be effective in treatment of neurodegenerative disorders.1
SU 4312 is a vascular endothelial growth factor (VEGF) receptor protein tyrosine kinase 1/2 and platelet derived growth factor (PDGF) receptor inhibitor.
特点和优势
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
其他说明
This product is a mixture of the cis- and trans- isomers. The ratio is about 55:45 based on HPLC.
基本信息
| 经验(实验)分子式 | C17H16N2O |
| 分子量 | 264.32 |
| MDL编号 | MFCD00118147 |
| PubChem化学物质编号 | 24278803 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | orange |
| 溶解性 | DMSO: >10 mg/mL H2O: insoluble |
| 储存温度 | 2-8℃ |
| SMILES string | CN(C)c1ccc(cc1)\C=C2\C(=O)Nc3ccccc23 |
| InChI | 1S/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-15-14-5-3-4-6-16(14)18-17(15)20/h3-11H,1-2H3,(H,18,20)/b15-11+ |
| InChI key | UAKWLVYMKBWHMX-RVDMUPIBSA-N |
| Gene Information | human ... FLT1(2321) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
