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VU591

品牌
Sigma-Aldrich
CAS
1222810-74-3
货号
SML0077
规格纯度
≥98% (HPLC)
参考价格
1505.41 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

VU591 may be used in cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

VU591 is a Potassium Inwardly-Rectifying Channel (KCNJ1 or ROMK) specific inhibitor (IC50 = 240 nM) that is closely related to VU590. Unlike VU590, VU591 does not inhibit Kir7.1. The compound has a modest effect on Kir6.2/SUR1, causing 17% inhibition at 10 uM.

特点和优势

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C16H12N6O5
分子量368.30
PubChem化学物质编号329825139
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to tan
溶解性DMSO: ≥12 mg/mL
储存温度2-8℃
SMILES string[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1
InChI1S/C16H12N6O5/c23-21(24)9-1-3-11-13(5-9)19-15(17-11)7-27-8-16-18-12-4-2-10(22(25)26)6-14(12)20-16/h1-6H,7-8H2,(H,17,19)(H,18,20)
InChI keyZQPXNYLXYNRFNP-UHFFFAOYSA-N
Gene Informationhuman ... KCNJ1(3758)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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