产品介绍:
产品说明
应用
Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells.
包装
5, 25 mg in glass bottle
生化/生理作用
Sal003 inhibits the late long-term potentiation (L-LTP) and long-term memory formation in mammalian hippocampal slices. The effect of Sal003 on L-LTP is mediated by the transcription factor, ATF4.
Sal003 is a potent and cell-permeable eIF-2a phosphatase inhibitor.
基本信息
经验(实验)分子式 | C18H15Cl4N3OS |
分子量 | 463.21 |
MDL编号 | MFCD00361095 |
PubChem化学物质编号 | 329824543 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | desiccated protect from light |
颜色 | white to off-white |
溶解性 | DMSO: ≥10 mg/mL |
相容性 | for use with Bio-Rad CFX96 |
储存温度 | 2-8℃ |
SMILES string | Clc1ccc(NC(=S)NC(NC(=O)\C=C\c2ccccc2)C(Cl)(Cl)Cl)cc1 |
InChI | 1S/C18H15Cl4N3OS/c19-13-7-9-14(10-8-13)23-17(27)25-16(18(20,21)22)24-15(26)11-6-12-4-2-1-3-5-12/h1-11,16H,(H,24,26)(H2,23,25,27)/b11-6+ |
InChI key | TVNBASWNLOIQML-IZZDOVSWSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H410 |
预防措施声明 | P273 - P501 |
危险分类 | Aquatic Acute 1 - Aquatic Chronic 1 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |