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Sal003

品牌
Sigma-Aldrich
CAS
1164470-53-4
货号
S4451
规格纯度
≥98% (HPLC)
参考价格
1746.39 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Sal003 was used to study the role of eIF2α in Subtilase cytotoxin-induced apoptosis in HeLa cells.

包装

5, 25 mg in glass bottle

生化/生理作用

Sal003 inhibits the late long-term potentiation (L-LTP) and long-term memory formation in mammalian hippocampal slices. The effect of Sal003 on L-LTP is mediated by the transcription factor, ATF4.
Sal003 is a potent and cell-permeable eIF-2a phosphatase inhibitor.

基本信息

经验(实验)分子式C18H15Cl4N3OS
分子量463.21
MDL编号MFCD00361095
PubChem化学物质编号329824543

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
protect from light
颜色 white to off-white
溶解性DMSO: ≥10 mg/mL
相容性for use with Bio-Rad CFX96
储存温度2-8℃
SMILES stringClc1ccc(NC(=S)NC(NC(=O)\C=C\c2ccccc2)C(Cl)(Cl)Cl)cc1
InChI1S/C18H15Cl4N3OS/c19-13-7-9-14(10-8-13)23-17(27)25-16(18(20,21)22)24-15(26)11-6-12-4-2-1-3-5-12/h1-11,16H,(H,24,26)(H2,23,25,27)/b11-6+
InChI keyTVNBASWNLOIQML-IZZDOVSWSA-N

安全信息

象形图GHS09
警示用语:Warning
危险声明H410
预防措施声明P273 - P501
危险分类Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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