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PP121

品牌
Sigma-Aldrich
CAS
1092788-83-4
货号
P0036
包装型号
规格纯度
≥98% (HPLC)
参考价格
1989.26 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases.
PP121 blocks the vascular endothelial growth factor (VEGF) receptor and its related signaling events. It also inhibits tumor cell proliferation by targeting oncogenic tyrosine kinase and phosphoinositide 3-kinases (PI3Ks).

特点和优势

This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphoinositide Kinases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C17H17N7
分子量319.36
MDL编号MFCD12912434
PubChem化学物质编号329819987
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 off-white
溶解性DMSO: >10 mg/mL
储存温度2-8℃
SMILES stringNc1ncnc2n(nc(-c3cnc4[nH]ccc4c3)c12)C5CCCC5
InChI1S/C17H17N7/c18-15-13-14(11-7-10-5-6-19-16(10)20-8-11)23-24(12-3-1-2-4-12)17(13)22-9-21-15/h5-9,12H,1-4H2,(H,19,20)(H2,18,21,22)
InChI keyNVRXTLZYXZNATH-UHFFFAOYSA-N

安全信息

储存分类代码6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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