产品说明
一般描述
C18 Dihydroceramide (d18:0/18:0) or N-Stearoylsphinganine is a synthetic lipid. Acylation of sphinganine with stearoyl (FA-CoA with C18 acyl chain) by dihydro ceramide synthase 1, yields C18-dihydroceramide.
应用
C18 Dihydroceramide (d18:0/18:0) has been used as a standard for the quantitation of sphingolipid metabolites in adipose tissues by quadrupole time-of-flight (Q-TOF) mass spectrometry.
生化/生理作用
Dihydroceramides act as precursors for ceramides in the mammalian de-novo sphingolipid pathway. vitamin D supplementation increases plasma C18 dihydroceramide (C18-DHC) levels in type 2 diabetes mellitus (T2D) patients. Low serum concentration of C18-DHC has been observed in patients with history of graft rejection and ischemic type biliary lesions (ITBL). Therefore, it can be used as a predictor of graft rejection.
包装
5 mL Amber Glass Screw Cap Vial (860627P-25mg)
5 mL Amber Glass Screw Cap Vial (860627P-5mg)
基本信息
| 经验(实验)分子式 | C36H73NO3 |
| 分子量 | 567.97 |
产品性质
| 形式 | powder |
| 包装 | pkg of 1 × 25 mg (860627P-25mg) pkg of 1 × 5 mg (860627P-5mg) |
| manufacturer/tradename | Avanti Polar Lipids 860627P |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| SMILES string | OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
