C18 Dihydroceramide (d18:0/18:0)

产品介绍：

产品说明

一般描述

C18 Dihydroceramide (d18:0/18:0) or N-Stearoylsphinganine is a synthetic lipid. Acylation of sphinganine with stearoyl (FA-CoA with C18 acyl chain) by dihydro ceramide synthase 1, yields C18-dihydroceramide.

应用

C18 Dihydroceramide (d18:0/18:0) has been used as a standard for the quantitation of sphingolipid metabolites in adipose tissues by quadrupole time-of-flight (Q-TOF) mass spectrometry.

生化/生理作用

Dihydroceramides act as precursors for ceramides in the mammalian de-novo sphingolipid pathway. vitamin D supplementation increases plasma C18 dihydroceramide (C18-DHC) levels in type 2 diabetes mellitus (T2D) patients. Low serum concentration of C18-DHC has been observed in patients with history of graft rejection and ischemic type biliary lesions (ITBL). Therefore, it can be used as a predictor of graft rejection.

包装

5 mL Amber Glass Screw Cap Vial (860627P-25mg)
5 mL Amber Glass Screw Cap Vial (860627P-5mg)

基本信息

经验(实验)分子式	C₃₆H₇₃NO₃
分子量	567.97

产品性质

形式	powder
包装	pkg of 1 × 25 mg (860627P-25mg) pkg of 1 × 5 mg (860627P-5mg)
manufacturer/tradename	Avanti Polar Lipids 860627P
运输	dry ice
储存温度	−20℃
SMILES string	OC[C@]([H])(NC(CCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)CCCCCCCCCCCCCCC

安全信息

储存分类代码

13 - Non Combustible Solids