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SGC-GAK-1N

品牌
Sigma-Aldrich
货号
SML2203
规格纯度
≥98% (HPLC)
参考价格
1048.99 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

SGC-GAK-1N (CA71) is a structure analog of and the recommended negative control for the ATP-competitive cyclin G-associated kinase (GAK) inhibitor SGC-GAK-1 (CA93) (GAK KD = 1.9 nM/SGC-GAK-1 vs. 7.1 μM/SGC-GAK-1N by ligand competitive binding assay; GAK IC50 = 110 nM/SGC-GAK-1 vs. >50 μM/SGC-GAK-1N by cellular target engagement assay; Dengue viral entry and packaging IC50 = 920 nM/SGC-GAK-1 vs. >10 μM/SGC-GAK-1N). For characterization details of the active probe, SGC-GAK-1, please visit the SGC-GAK-1 probe summary on the Structural Genomics Consortium (SGC) website.

SGC-GAK-1, the active probe, is available from Sigma. To learn more about and purchase SGC-GAK-1, click here.

To learn about other SGC chemical probes, visit sigma.com/sgc

特点和优势

SGC-GAK-1N is a negative control for SGC-GAK-1, a chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC chemical probes, visit sigma.com/SGC

基本信息

经验(实验)分子式C20H19F3N2O3
分子量392.37
NACRESNA.77

产品性质

测定≥98% (HPLC)
形式powder
颜色dark green to black
溶解性DMSO: 2 mg/mL, clear
储存温度2-8℃
SMILES stringCN(C1=CC(OC)=C(OC)C(OC)=C1)C2=C3C(C=CC(C(F)(F)F)=C3)=NC=C2

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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