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SM-19712 hydrate

品牌
Sigma-Aldrich
CAS
194542-56-8
货号
S3445
规格纯度
≥98% (HPLC)
参考价格
2266.84 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

SM-19712 hydrate was used in studies to determine the effectiveness of ECE inhibition as a treatment option for Alzheimer′s disease.

包装

5, 25 mg in glass bottle

生化/生理作用

SM-19712 a sulfonylureid-pyrazole derivative is a potent and selective inhibitor of endothelin converting enzyme (ECE). It attenuates the effects of ischemic acute renal failure and reduces the inflammation, tissue injury and vasoconstriction induced by dextran sodium sulfate in mouse colon.
Nonpeptide, potent and selective endothelin converting enzyme inhibitor.

基本信息

经验(实验)分子式C18H13ClN5NaO3S · xH2O
分子量437.84 (anhydrous basis)
MDL编号MFCD06798351
PubChem化学物质编号329824532
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 off-white to light brown
溶解性DMSO: ≥20 mg/mL
H2O: ≥20 mg/mL
储存温度2-8℃
SMILES stringClC1=CC=C(S(N(C(NC2=C(C#N)C(C)=NN2C3=CC=CC=C3)=O)[Na])(=O)=O)C=C1
InChI1S/C12H10ClN5O3S.Na.H2O/c1-7-10(6-14)11(17-16-7)15-12(19)18-22(20,21)9-4-2-8(13)3-5-9;;/h2-5H,1H3,(H3,15,16,17,18,19);;1H2/q;+1;/p-1
InChI keyHLHPDQXMLDUDQV-UHFFFAOYSA-M

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves

Sigma-Aldrich

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