产品介绍:
产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
Qc1 is a reversible inhibitor of threonine dehydroxygenase (TDH). The IC50 value for inhibition of TDH by Qc1 is 500 nM, with no detectable inhibition of other dehydroxygenase enzymes at concentrations up to 10 mM. Qc1 induces arrest and autophagy of mouse ES cells with an EC50 of 3 mM.
基本信息
经验(实验)分子式 | C23H16F3N3O2S |
分子量 | 455.45 |
MDL编号 | MFCD02649259 |
PubChem化学物质编号 | 329825432 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 5 mg/mL (clear solution, warmed) |
储存温度 | 2-8℃ |
SMILES string | FC(F)(F)c1cccc(c1)N2C(=S)Nc3cc(ccc3C2=O)C(=O)NCc4ccccc4 |
InChI | 1S/C23H16F3N3O2S/c24-23(25,26)16-7-4-8-17(12-16)29-21(31)18-10-9-15(11-19(18)28-22(29)32)20(30)27-13-14-5-2-1-3-6-14/h1-12H,13H2,(H,27,30)(H,28,32) |
InChI key | IFNVTSPDMUUAFY-UHFFFAOYSA-N |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |