产品说明
生化/生理作用
PTEN, a tumor suppressor, has been implicated in a large number of human tumors and is conserved from humans to worms. Characterization of PTEN protein showed that it is a phosphatase that acts on proteins and on 3-phosphorylated phosphoinositides, and can therefore modulate signal-transduction pathways that involve lipid second messengers. Recent results indicate that at least part of its role is to regulate the activity of the serine/threonine kinase AKT/PKB, and thus influence cell survival signaling. Recombinant PTEN is purified by proprietary chromatographic techniques.
外形
Sterile filtered liquid at 100 μg/ml.
重悬
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
MDL编号 | MFCD03458266 |
NACRES | NA.32 |
产品性质
生物来源 | human |
重组 | expressed in E. coli |
测定 | ≥90% |
形式 | liquid |
分子量 | ~86.0 kDa |
包装 | pkg of 5 μg |
储存条件 | avoid repeated freeze/thaw cycles |
杂质 | <0.1 EU/μg |
NCBI登记号 | P60484 |
运输 | dry ice |
储存温度 | −70℃ |
Gene Information | human ... PTEN(5728) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |