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InSolution Purmorphamine-Calbiochem

品牌
Sigma-Aldrich
货号
540223
规格纯度
Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
参考价格
2942.34 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Purmorphamine is a cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells.
A cell-permeable purine compound that induces osteoblast differentiation in C3H10T1/2 multipotent mesenchymal progenitor cells (EC50 = 1 µM) and in MC3T3-E1 lineage-committed preosteoblasts. Also shown to induce transdifferentiation in pre-adipocytes and myoblasts. Its effects are reported to be synergistic with bone morphogenetic protein-4 (BMP-4). Reported to induce osteogenesis by activation of the Hedgehog signaling pathway.

包装

5 mg in Plastic ampoule
Packaged under inert gas

应用

InSolution Purmorphamine, CAS 483367-10-8, is a provided as a 50 mM solution in DMSO. Induces osteoblast differentiation of multipotent mesenchymal progenitor cells C3H10T1/2 & lineage-committed preosteoblasts MC3T3-E1.

警告

Toxicity: Irritant (B)

外形

A 50 mM (5 mg/192 µl) solution of Purmorphamine (Cat. No. 540220) in DMSO.

重悬

Following initial thaw, aliquot and freeze (-20°C).

其他说明

Wu, X., et al. 2004. Chem. Biol.11, 1229.
Wu, X., et al. 2002. J. Am. Chem. Soc.124, 14520.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质

质量水平100
测定≥98% (HPLC)
形式liquid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
desiccated (hygroscopic)
protect from light
储存温度−20℃

安全信息

象形图GHS08
警示用语:Warning
危险声明H341
预防措施声明P201 - P202 - P280 - P308 + P313 - P405 - P501
危险分类Muta. 2
储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)188.6 °F
闪点(C)87 ℃

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