产品说明
包装
1, 5 mg in glass bottle
生化/生理作用
Arglabin is a natural product with antitumor and anti-inflammatory activity. Arglabin competitively inhibits the binding of farnesyl diphosphate to farnesyl transferase (FTase), preventing the activation of RAS proto-oncogene by preventing the incorporation of farnesyl pyrophosphate into human H-ras proteins. Arglabin is also an inhibitor of the NLRP3 inflammasome. Arglabin reduces inflammation and plasma lipids and has shown a marked reduction in atherosclerotic lesions.
基本信息
经验(实验)分子式 | C15H18O3 |
分子量 | 246.30 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
生物来源 | semisynthetic (from parthenolide) |
测定 | ≥98% (HPLC) |
形式 | powder |
储存条件 | protect from light |
颜色 | white to beige |
储存温度 | −20℃ |
InChI | 1S/C15H18O3/c1-8-4-7-15-11(8)12-10(9(2)13(16)17-12)5-6-14(15,3)18-15/h4,10-12H,2,5-7H2,1,3H3/t10-,11-,12-,14-,15+/m0/s1 |
InChI key | UVJYAKBJSGRTHA-ZCRGAIPPSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 - H315 - H319 - H335 |
预防措施声明 | P301 + P312 + P330 - P305 + P351 + P338 |
危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
靶器官 | Respiratory system |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |