产品说明
一般描述
Cyrene™ γ-Valerolactone Blend is specially formulated for use in automated processes and applications where lower viscosity is required, making it easier to handle while maintaining high yields.
This Cyrene™ blend is an alternative for NMP and DMF in many cross-coupling reactions. Neither Cyrene™ nor γ-Valerolactone have any genotoxic or mutagenic concerns associated with their use, making them much safer alternatives to traditional aprotic solvents.
This new blend is part of our Biorenewable product line, meaning that it is made from renewable resources and does not compete with food resources for its production, making it more environmentally sustainable for the future. The material has also been independently certified as 100% renewable carbon.
应用
This cosolvent solution has been shown to have similar reaction yields to NMP and DMF for many cross-coupling reactions, such as:
- HATU Amide Coupling - Replacement for DMF in amide and dipeptide coupling reactions (eq. 1)
- Suzuki-Miyaura coupling reaction (eq. 2)
- Sonogashira coupling reaction (eq. 3)
特点和优势
- Independently certified as 100% renewable carbon.
- Closer physical properties of NMP and DMF while maintaining high reaction yields.
- Sustainably produced and environmentally less hazardous than more traditional petroleum aprotic solvents
- Both Cyrene™ and GVL are also much safer for handling without the genotoxic concerns of other solvents.
- It has a lower viscosity than neat Cyrene™ making it more optimized for automated processes. (See Table 2)
其他说明
To see other BioRenewable or Greener Solvents
法律信息
CYRENE is a trademark of Circa Group Pvt Ltd
基本信息
经验(实验)分子式 | C6H8O3 |
分子量 | 128.13 |
产品性质
形式 | liquid |
环保替代产品特性 | Safer Solvents and Auxiliaries Use of Renewable Feedstocks Learn more about the Principles of Green Chemistry. |
密度 | 1.141 g/mL |
环保替代产品分类 | Aligned |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H319 |
预防措施声明 | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
危险分类 | Eye Irrit. 2 |
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |