产品说明
一般描述
Albumin is the most abundant plasma protein in human. It has a molecular weight of 66.5 kDa.
应用
Albumin from human serum has been used:
- as a carrier of CPT-11 (irinotecan, Campto) and SN-38 to investigate its binding to human plasma proteins
- to study the adsorption of water and acetonitrile (AN) vapor on a human serum albumin
- to study its effect on wound healing process
包装
100, 500 mg in poly bottle
1, 5, 10, 25 g in poly bottle
生化/生理作用
血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白,对调节血液的胶体渗透压至关重要。研究还发现白蛋白可结合外源物质,特别是药物(例如布洛芬、华法林),并强烈影响其药代动力学。导致白蛋白氧化还原状态变化的氧化应激对其生理功能具有广泛的影响。
Serum albumin primarily mediates divalent cation transportation, fatty acid and drug complex formation and transport. The albumin levels in the serum indicate the disease progression in advanced liver disease. Low body weight and decreased serum albumin is associated with colorectal cancer.
制备说明
Prepared from albumin (A1653)
其他说明
查看更多关于 人血清白蛋白的信息。
基本信息
EC 号 | 274-272-6 |
MDL编号 | MFCD00081418 |
eCl@ss | 42010201 |
产品性质
质量水平 | 300 |
生物来源 | human |
测定 | ≥96% (agarose gel electrophoresis) |
形式 | lyophilized powder |
分子量 | monomer calculated mol wt 66478 Da |
technique(s) | ELISA: suitable tissue culture: suitable western blot: suitable |
杂质 | HIV I and HIVII, HCV and HBsAg, tested negative ≤0.007% Fatty Acids |
溶解性 | H2O: soluble 50 mg/mL, clear to slightly hazy |
UniProt登记号 | P02768 |
储存温度 | 2-8℃ |
Gene Information | human ... ALB(213) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves |