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Verapamil Hydrochloride

(±)-维拉帕米 盐酸盐

CAS
152-11-4
货号
V0100000
规格纯度
European Pharmacopoeia (EP) Reference Standard
参考价格
1572.27 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

α1-肾上腺素受体拮抗剂;L型钙通道阻滞剂。阻断平滑肌和心肌中的 L 型 Ca2+ 通道,体外诱导人原发性和转移性结肠癌细胞的凋亡。对 PGP 起作用的抗药性逆转剂,如减少肾小管清除地高辛。增加 Pgp 的基础 ATP 酶活性。Cyp3A4 和 CYP2C6 的底物。

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式(CH3O)2C6H3CH2CH2N(CH3)(CH2)3C[C6H3(OCH3)2][CH(CH3)2]CN · HCl
分子量491.06
Beilstein3647093
MDL编号MFCD00055208
PubChem化学物质编号329828921
NACRESNA.24

产品性质

等级pharmaceutical primary standard
agencyEP Reference Standard
manufacturer/tradenameEDQM
mp142 ℃ (dec.) (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl.COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC
InChI1S/C27H38N2O4.ClH/c1-20(2)27(19-28,22-10-12-24(31-5)26(18-22)33-7)14-8-15-29(3)16-13-21-9-11-23(30-4)25(17-21)32-6;/h9-12,17-18,20H,8,13-16H2,1-7H3;1H
InChI keyDOQPXTMNIUCOSY-UHFFFAOYSA-N
Gene Informationhuman ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

安全信息

象形图GHS06GHS09
警示用语:Danger
危险声明H301 - H411
预防措施声明P264 - P270 - P273 - P301 + P310 - P391 - P405
危险分类Acute Tox. 3 Oral - Aquatic Chronic 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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