Proteasome Inhibitor Set II-Calbiochem

产品说明

一般描述

Proteasomes are large multi-subunit protease complexes, which selectively degrade intracellular proteins. A protein marked for degradation is attached to multiple molecules of ubiquitin, a 76-amino acid protein, which escorts it for rapid hydrolysis, by the 26S proteasome. The proteolytic core of this complex consists of the 20S proteasome, which contains multiple peptidase activities and has a molecular mass of ~700 kDa. Recently several potent, cell-permeable proteasome inhibitors have been developed.



The Calbiochem brand offers a set that includes 3 proteasome inhibitors with varying inhibtory effects.



The table below outlines some of the physical and biological properties of these compounds.
Contains 5 mg of ALLN (Cat. No. 208719), 100 μg each of Epoxomicin (Cat. No. 324800), and clasto-Lactacystin β-Lactone (Cat. No. 426102). Supplied with a data sheet.

包装

1 set in Glass bottle
Packaged under inert gas

生化/生理作用

Secondary Target
cathepsin B, cathepsin L
Primary Target
calpain 1, calpain 2

警告

Toxicity: Standard Handling (A)

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

产品性质