MDA-MB-468人乳腺癌细胞

产品介绍

目录号 Serial	TCHu136
标识符 Identifier	CSTR:19375.09.3101HUMTCHu136
描述 Description	1977年由R. Cailleau等从一位患有乳腺癌的51岁黑人女性转移癌胸水中分离得到。虽然供组织者的G6PD等位基因杂合，但此细胞株始终表现为G6PD A表型。在本库通过支原体检测。在本库通过STR检测。
动物种别 Organism	人
性别 Gender	女
组织来源 Tissue and Cell Type	乳腺，乳房，腺癌
形态 Morphology	上皮细胞
培养基和添加剂 Complete Growth Medium and Culture Conditions	L-15培养基(GIBCO,货号41300039)，90%；优质胎牛血清，10%。气相：空气，100%。温度：37摄氏度。
供应限制 Permits and Restrictions	A。仅供研究之用。
REFERENCE	Brinkley BR , et al. Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro. Cancer Res. 40: 3118-3129, 1980. PubMed: 7000337Siciliano MJ , et al. Mutually exclusive genetic signatures of human breast tumor cell lines with a common chromosomal marker. Cancer Res. 39: 919-922, 1979. PubMed: 427779Pathak S , et al. A human breast adenocarcinoma with chromosome and isoenzyme markers similar to those of the HeLa line. J. Natl. Cancer Inst. 62: 263-271, 1979. PubMed: 283262Cailleau R , et al. Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 14: 911-915, 1978. PubMed: 730202Nigro JM , et al. Mutations in the p53 gene occur in diverse human tumour types. Nature 342: 705-707, 1989. PubMed: 2531845Bates SE , et al. Expression of the transforming growth factor-alpha/epidermal growth factor receptor pathway in normal human breast epithelial cells. Endocrinology 126: 596-607, 1990. PubMed: 2294006Avila MA , et al. Quercetin mediates the down-regulation of mutant p53 in the human breast cancer cell line MDA-MB468. Cancer Res. 54: 2424-2428, 1994. PubMed: 8162591Littlewood-Evans AJ , et al. The osteoclast-associated protease cathepsin K is expressed in human breast carcinoma. Cancer Res. 57: 5386-5390, 1997. PubMed: 9393764Zamora-Leon SP , et al. Expression of the fructose transporter GLUT5 in human breast cancer. Proc. Natl. Acad. Sci. USA 93: 1847-1852, 1996. PubMed: 8700847

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