MCF7 [MCF-7]人乳腺癌细胞
产品介绍
目录号 Serial | TCHu 74 | 标识符 Identifier | CSTR:19375.09.3101HUMTCHu74 | 描述 Description | MCF-7细胞保留了多个分化了的乳腺上皮的特性,包括:能通过胞质雌激素受体加工雌二醇并能形成圆形复合物(domes)。 该细胞含有Tx-4癌基因。 肿瘤坏死因子α(TNF alpha)可以抑制MCF-7细胞的生长。 抗雌激素处理细胞能调变IGFBP’S的分泌。 在本库通过支原体检测。 在本库通过STR检测。 | 动物种别 Organism | 人 | 性别 Gender | 女 | 组织来源 Tissue and Cell Type | 腺癌,乳腺,胸水。 | 形态 Morphology | 上皮细胞 | 培养基和添加剂 Complete Growth Medium and Culture Conditions | MEM培养基(GIBCO,货号41500034,添加NaHCO3 1.5g/L,Sodium Pyruvate 0.11g/L,0.01mg/ml bovine insulin),90%;优质胎牛血清,10%。 气相:空气,95%;二氧化碳,5%。 温度:37摄氏度。 | 供应限制 Permits and Restrictions | A。仅供研究之用。 | REFERENCE | Sugarman BJ , et al. Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 230: 943-945, 1985. PubMed: 3933111Takahashi K , Suzuki K . Association of insulin-like growth-factor-I-induced DNA synthesis with phosphorylation and nuclear exclusion of p53 in human breast cancer MCF-7 cells. Int. J. Cancer 55: 453-458, 1993. 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