Technical Notes:

1.Grubbs-2 catalyst used in conjunction with the lypophilic amphiphile TPGS-750-M . for ring closing and cross- metathesis reactions in water, at room temperature.

2. A variety of widely used palladium-catalyzed, cross- coupling reactions (including Heck, SuzukiMiyaura, Sonogashira, and Buchwald-Hartwig aminations) can be run under mild, ambient conditions in water with TPGS-750-M