产品说明
一般描述
KIN is a nuclear protein that forms intranuclear foci during cell proliferation. KIN is re-distributed in the nucleoplasm during the course of the cell cycle. This protein may also be involved in cell repair following UV-induced DNA damage.
Rabbit Anti-KIN antibody recognizes bovine, canine, and human KIN.
免疫原
Synthetic peptide directed towards the middle region of human KIN
应用
Rabbit Anti-KIN antibody can be used for western blot (0.25-5.0μg/ml) and immunohistochemistry (4-8μg/ml, paraffin-embedded tissues) applications.
生化/生理作用
Kin is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by the human ortholog.
序列
Synthetic peptide located within the following region: LKTIGSSASVKRKESSQSSTQSKEKKKKKSALDEIMEIEEEKKRTARTDY
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 45 kDa |
| species reactivity | horse, human |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI登记号 | NP_036443 |
| UniProt登记号 | O60870 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KIN(22944) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
