Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4

产品说明

一般描述

Nectin-3, also known as Poliovirus receptor-related protein 3 (PVRL3) and PRR3, is thought to work with cadherin to form cell-cell adherens junctions. It is a transmembrane protein that is commonly found in the testis and in placental tissue. Nectin-3 colocalizes with CD155, the cognate receptor for poliovirus, to cell-cell junctions. Nectin-3′s involvement in down-regulation PVR from the cell surface leads to a reduction in cell motility and proliferation.

免疫原

Full length recombinant protein corresponding to human Nectin-3.

应用

Research Category
Cell Structure
Anti-Nectin-3/PVRL3 (CD113) Antibody, clone N3.12.4 detects level of Nectin-3/PVRL3 (CD113) & has been published & validated for use in FC.
Research Sub Category
ECM Proteins

质量

Evaluated by Flow Cytometry in U251 cells.

Flow Cytometry Analysis: 0.1 µg of this antibody detected Nectin-3 in U251 cells.

目标描述

61 kDa calculated

外形

Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
U251 cells

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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