产品说明
一般描述
IL-8 (interleukin-8), also called CXCL8, is an α chemokine belonging to the cysteine-x-cysteine (CXC) chemokine subfamily. It is a pro-inflammatory cytokine and is secreted by multiple types of tissues and blood cells such as, monocytes, neutrophils, tissue macrophages, T-lymphocytes, endothelial and epithelial cells, and fibroblasts. It is pro-angiogenic and tumorigenic, and is produced by cancer cells such as, colorectal cancer cells.
免疫原
Recombinant interleukin-8
Immunogen Sequence: GI # 124359, sequence 28-99
应用
Anti-Interleukin-8 antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Interleukin-8 (IL 8) is a proinflammatory chemokine that activates multiple signaling pathways. The exosomes released from chronic myelogenous leukemia (CML) cells stimulate bone marrow stromal cells to produce IL 8. It plays a very important regulatory function in tumorigenesis. Its polymorphism is associated with a significantly increased risk of cancers and may be useful for cancer susceptibility studies.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD00212220 |
| NACRES | NA.41 |
产品性质
| 生物来源 | chicken |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | human |
| manufacturer/tradename | Genway 15-288-21030 |
| technique(s) | indirect ELISA: suitable western blot: suitable |
| NCBI登记号 | P10145 |
| UniProt登记号 | P10145 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... IL8(3576) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
| 个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
