Anti-M6PR antibody produced in chicken

产品说明

免疫原

Immunogen Sequence: GI # 4505061, sequence 60-114
Recombinant cation-dependent mannose-6-phosphate receptor

应用

Anti-M6PR antibody produced in chicken is suitable for immunocytochemistry and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Mannose 6-phosphate receptor is an integral transmembrane glycoprotein encoded by the M6PR gene in humans. It is ubiquitously expressed and are distinguished from all other lectins by their ability to recognize phosphorylated mannose residues. It is a 46kDa cation-dependent mannose 6-phosphate receptor (CD-MPR) and plays a key role in the delivery of lysosomal enzymes to the lysosome by binding newly synthesized mannose 6-phosphate (Man-6-P)-containing acid hydrolases and diverting them from the secretory pathway. M6PR plays a major role in cellular function by transporting Man-6-P-containing acid hydrolases from the Golgi to endosomal/lysosomal compartments.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息