产品说明
一般描述
CD349 is a member of the Frizzled family, known as Frizzled-9 (Fz9, FZD9, hFz9, or FzE6) which was originally described as FZD3. Ten frizzled member have been identified in humans. FZD9 is a seven transmembrane G-protein-coupled receptor (GPCR), a receptor for Wnt proteins. It is involved in the activation of Wnt/β-catenin pathway (canonic Wnt signaling). FZD9 is predominately expressed in fetal and adult brain, testis, eye, skeletal muscle and kidney and is also expressed on Mesenchymal stem cells, and neural precursor cells. Frizzled proteins play important roles in controlling cell fate, proliferation, migration, tissue architecture and organogenesis during embryonic development and in adult organisms. FZD9 is an important factor for nervous system development and is critical for hippocampal development.
免疫原
Whole WERI-RB-1 cells
应用
Research Category
Stem Cell Research
Stem Cell Research
Anti-CD349/Frizzled 9 Antibody, clone W3C4 is an antibody against CD349/Frizzled 9 for use in Flow Cytometry.
Research Sub Category
Pluripotent & Early Differentiation
Developmental Signaling
质量
Evaluated by Flow Cytometry on WERI-RB-1 cells Flow Cytometry Analysis: 4 µg/mL of this antibody detected CD349/Frizzled 9 on 1X10^5 WERI-RB-1 cells.
目标描述
65 kDa calculated
外形
Purified by Ion-Exchange Chromatography
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
WERI-RB-1 cells
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | W3C4-hMSC, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable |
| 同位素/亚型 | IgMκ |
| NCBI登记号 | NP_003499 |
| UniProt登记号 | O00144 |
| 运输 | wet ice |
| Gene Information | human ... FZD9(8326) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
