产品说明
免疫原
Recombinant decay accelerating factor for complement
Immunogen Sequence: GI # 10835143, sequence 36-129
应用
Anti-CD55 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生化/生理作用
Complement decay-accelerating factor (decay-accelerating factor, DAF) is a protein encoded by the CD55 gene in humans. It plays multiple functions including tissue protection from the cytotoxic complement injury and an anti-inflammatory function due to its anti-adherence properties. It is essential in many organ systems including pregnancy for protection of the semiallogeneic fetus or for preventing uncontrolled infiltration by white cells in their pro- and/or anti-inflammatory functions. Expression of CD55 appears to have multiple regulatory tissue-specific and/or menstrual cycle-specific mechanisms that are involved in complex signaling mechanisms. Its regulation may involve a direct or an indirect effect of at least the estrogen, progesterone, and corticosteroid regulatory pathways. It plays a a primary role in conferring resistance to lysis. CD55 is overexpressed in several types of cancer.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
MDL编号 | MFCD00675552 |
NACRES | NA.41 |
产品性质
生物来源 | chicken |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | human |
manufacturer/tradename | Genway 15-288-22692 |
technique(s) | western blot: suitable |
NCBI登记号 | NP_000565.1 |
UniProt登记号 | P08174 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... CD55(1604) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
个人防护装备 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |