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Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone)

品牌
Sigma-Aldrich
货号
915599
规格纯度
PEG average Mn 2,000, PCL average Mn 5,000
参考价格
1356.47 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

Carboxylic acid-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The carboxylic acid functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

基本信息

线性分子式C3H5O3[C2H4O]n[C6H10O2]mH

产品性质

质量水平100
形式powder or chunks
分子量PCL average Mn 5,000 (by NMR)
PCL average Mn 5,000
PEG average Mn 2,000 (by NMR)
PEG average Mn 2,000
颜色 white to beige
PDI≤1.3 (by GPC)
储存温度−20℃
SMILES string[H]OCCCCCC(OCCOCCC(O)=O)=O

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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