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Anti-KCNN3 (AB1) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV35097
规格纯度
affinity isolated antibody
参考价格
6889.23 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

KCNN3 (SK3) codes for a voltage-independent, calcium-activated channel integral membrane protein. It may be involved in the modulation of neuronal excitability. KCNN3 has been linked to anorexia nervosa risk and atrial fibrillation.
Rabbit Anti-KCNN3 antibody recognizes canine, human, mouse, rat, pig, and bovine KCNN3.

免疫原

Synthetic peptide directed towards the C terminal region of human KCNN3

应用

Rabbit Anti-KCNN3 antibody is suitable for western blot assays at 2 μg/ml.

生化/生理作用

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.

序列

Synthetic peptide located within the following region: ITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSA

外形

 Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 81 kDa
species reactivityrabbit, dog, bovine, rat, mouse, guinea pig, human
浓度0.5 mg - 1 mg/mL
technique(s)immunohistochemistry: suitable
western blot: suitable
NCBI登记号NP_002240
UniProt登记号Q9UGI6
运输wet ice
储存温度−20℃
Gene Informationhuman ... KCNN3(3782)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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