产品说明
一般描述
The FOXO family of transcription factors mediates the interplay between the PI3K-Akt and TOR signaling. The PI3K-Akt-FoxO signaling axis has direct role in cell proliferation, oxidative stress, tumorigenesis and physiological processes.
免疫原
Synthetic peptide directed towards the N terminal region of human FOXO1
应用
Anti-FOXO1 (AB1) antibody produced in rabbit is suitable for western blotting at a concentration of 1 μg/ml.
生化/生理作用
FoxO1 mediates the signaling pathways that are involved in glucose metabolism. It is highly expressed in pancreas, liver, adipose and skeletal muscle tissue. The main role of FoxO1 is the maintenance of energy homeostasis during fasting, glycemic control and regulate the breakdown of carbohydrates. FoxO1 is a critical energy and nutrient regulator and is conserved across species.
序列
Synthetic peptide located within the following region: MAEAPQVVEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAA
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 70 kDa |
| species reactivity | human, pig, dog, bovine |
| 浓度 | 0.5 mg - 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_002006 |
| UniProt登记号 | Q12778 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... FOXO1(2308) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
