产品说明
一般描述
Recombinant, mouse α-interferon expressed in E. coli. Antiviral and anti-neoplastic agent. Suppresses bone marrow function and induces apoptotic cell death in non-melanoma skin cancer. IFN-α signaling is mediated by JAK1 and TYK2 tyrosine kinases. Note: 1 KU = 1000 units.
Recombinant, mouse α-interferon expressed in E. coli. Antiviral, antineoplastic agent. Expressed during the triggering stage of macrophage cytocidal activation. Suppresses bone marrow function and cell proliferation. Modulates the immune response. Also known to induce apoptotic cell death in non-melanoma skin cancer.
包装
100 ku in Plastic ampoule
警告
Toxicity: Standard Handling (A)
单位定义
One unit of interferon per ml of medium will cause a 50% inhibition of EMCV-induced cytopathic effect on mouse L929 cells. Units are determined with respect to the NIH international reference standard for mouse IFN-α.
其他说明
Krishnan, K., et al. 1997. Eur. J. Biochem. 247, 298.
Rodriquez-Villanueva, S., and McDonnel, T.J. 1995. Int. J. Cancer61, 110.
Dianzani, F. 1993. Gut34, 574.
Brouty-Boyce, D., and Zetter, B.R. 1990. Science208, 516.
Sidky, Y.A., and Borden, E.C. 1987. Cancer Res.47, 5155.
Daugherty, B.L., and Pestka, S. 1986. Methods Enzymol.119, 34.
Pestka, S. 1986. Methods Enzymol.119, 14.
Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Johnson, M.D., et al. 1981. Methods Enzymol.78, 394.
Rubinstein, S., et al. 1981. J. Virol.37, 755.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
产品性质
| 测定 | ≥95% (SDS-PAGE) |
| 质量水平 | 100 |
| 形式 | liquid |
| specific activity | ≥3.5 x 104 units/mL |
| manufacturer/tradename | Calbiochem® |
| 储存条件 | OK to freeze avoid repeated freeze/thaw cycles |
| 运输 | wet ice |
| 储存温度 | −70℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
