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SRC1, His tagged, TEV site, human

品牌
Sigma-Aldrich
货号
SRP2068
规格纯度
recombinant, expressed in E. coli, ≥80% (SDS-PAGE)
参考价格
6049.01 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

生化/生理作用

Steroid receptor coactivator 1 (SRC1) is a transcriptional coactivator that mediates the activating functions of many of the nuclear hormone receptors. It is also known as NCoA1 and is a member of the SRC/p160 coactivator family. SRC1 has been shown to be over expressed in some cancers. SRC1 is a 160 kDa protein that contains several LXXLL motifs, which are involved in nuclear receptor interaction. The region 627-786 contains 3 LXXLL motifs that are involved in interaction with nuclear hormone receptorsand have been previously used in assays detecting ligand-dependent receptor-cofactor interactions. This protein contains the Tobacco Etch virus (TEV) protease site and can be cleaved using acTEV to yield untagged SRC1 RID. This protein will be useful for assays where a native untagged protein is desired.

外形

Clear and colorless frozen liquid solution

制备说明

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

基本信息

NACRESNA.26

产品性质

生物来源human
重组expressed in E. coli
测定≥80% (SDS-PAGE)
形式frozen liquid
分子量 ~19.5 kDa
包装pkg of 10 μg
储存条件avoid repeated freeze/thaw cycles
浓度400 μg/mL
颜色clear colorless
NCBI登记号NM_003743
UniProt登记号Q15788
运输dry ice
储存温度−70℃
Gene Informationhuman ... NCOA1(8648)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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