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TAF1 (1371-1496) GST tag human

品牌
Sigma-Aldrich
货号
SRP6577
规格纯度
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
参考价格
3563.77 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. TAF1 is a component of transcription factor IID, and binds to core promoter sequences at the transcription start site. TAF1 helps control transcription by both its kinase and histone acetyltransferase enzymatic activities. It interacts with transcriptional activators such as the androgen receptor to promote transcription. Disruption of TAF1 causes dystonia 3 (X-linked torsion dystonia) and decreased apoptosis. This protein product contains the first bromodomain of TAF1.

外形

50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5 mM β-mercaptoethanol and 5% glycerol.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥95% (SDS-PAGE)
形式liquid
分子量 41.7 kDa (1371-1496 aa + NT GST Tag)
包装pkg of 100 μg
pkg of 20 μg
UniProt登记号P21675
运输dry ice
储存温度−70℃
Gene Informationhuman ... TAF1(6872)

安全信息

象形图GHS07
警示用语:Warning
危险声明H317 - H319 - H412
预防措施声明P273 - P280 - P305 + P351 + P338 - P333 + P313 - P337 + P313
危险分类Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

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